When on, Mudbox saves paint layers for all PTEX models in the scene as PTEX files in the <filename>-files folder associated with your .mud file. This process does slow the saving of .mud files that contain painted PTEX objects. See also Save or export paint layers.
When on (default), Mudbox also saves general data about the mesh (vertex positions, list of faces, and so on) in output PTEX files. This can be useful if other tools in your pipeline can use this type of PTEX data, for example if you will use a PTEX viewer to inspect the output file. It is recommended that you keep this option on if you plan to extract PTEX files.
When on, Mudbox automatically scans every FBX or OBJ mesh that you import to alert you to any potential problems before you spend time painting or sculpting. When off, imported files are not scanned. You can also select Mesh > Validate Meshes from the main menu bar at any time to scan all meshes in the scene.